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. 2023 Apr 21;15(8):2391. doi: 10.3390/cancers15082391

Table 1.

Patient characteristics 1.

Variable RATS
(n = 366)
VATS
(n = 380)
p Value
Age, years 69.7 ± 9.8 69.1 ± 9.9 0.373
Sex, n (%) 0.269
Female 234 (63.9) 228 (60.0)
Male 132 (36.1) 152 (40.0)
BMI, kg/m 2 27.5 ± 5.6 27.1 ± 5.3 0.289
Smoking status, n (%) 0.166
Non-smoker 81 (22.1) 63 (16.6)
Ex-smoker 219 (59.8) 254 (66.8)
Smoker 62 (16.9) 63 (16.6)
Unknown 3 (0.8)
Pulmonary function
FEV1% of predicted 91.9 ± 21.2 92.3 ± 22.3 0.790
FVC% of predicted 108.4 ± 20.8 108.9 ± 21.3 0.742
DLCO% of predicted 76.5 ± 20.1 72.2 ± 18.8 0.003
Comorbidities, n (%)
Atrial fibrillation 30 (8.2) 26 (6.8) <0.001
Bronchiectasis 6 (1.6) 0.012
Cerebrovascular accident 16 (4.4) 13 (3.4) 0.502
Chronic kidney disease 14 (3.8) 19 (5.0) 0.435
COPD 80 (21.9) 92 (24.2) 0.446
Coronary artery disease 47 (12.8) 51 (13.4) 0.815
Interstitial lung disease 1 (0.3) 5 (1.3) 0.111
Peripheral vascular disease 3 (0.8) 3 (0.8) 0.963
Previous other cancer 147 (40.2) 125 (32.9) 0.039
Previous primary lung cancer 18 (4.9) 19 (5.0) 0.959
Pulmonary hypertension 2 (0.5) 1 (0.3) 0.541
Charlson Comorbidity Index, 2 median (range) 6 (0–19) 6 (0–18) 0.977
Induction chemotherapy, n (%) 8 (2.2) 10 (2.6) 0.692
Histopathology, n (%) 0.820
Adenocarcinoma 226 (61.7) 217 (57.1)
Squamous cell carcinoma 49 (13.4) 63 (16.6)
Carcinoid tumor 34 (9.3) 24 (6.3%)
Other 57 (15.6) 76 (20)
Clinical stage, n (%)
0 2 (0.5) 1 (0.3)
IA1 23 (6.3) 16 (4.2)
IA2 83 (22.7) 98 (25.8)
IA3 65 (17.8) 43 (11.3)
IB 57 (15.6) 64 (16.8)
IIA 19 (5.2) 20 (5.3)
IIB 37 (10.1) 36 (9.5)
IIIA 24 (6.6) 32 (8.4)
IIIB 5 (1.4) 7 (1.8)
IIIC
IVA 1 (0.3) 1 (0.3)
IVB 1 (0.3)
Unknown 50 (13.7) 61 (16.1)

1 Plus–minus values are means ± standard deviations. 2 The Charlson Comorbidity Index quantifies an individual’s burden of disease, with scores ranging from 0 to 37; the higher the score, the more likely the predicted outcome will result in mortality or higher resource use. COPD, chronic obstructive pulmonary disease; DLCO, diffusing capacity of the lungs for carbon monoxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.