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(A) Schematic representation of human CHD proteins subfamilies, showing the approximate size and all known or predicted domains. (B) The NuRD complex. The primary components of the NuRD complex include the ATP-dependent remodelling enzymes CHD3/4/5, the histone deacetylases HDAC1/2, the scaffold proteins MTA1/2/3, the histone chaperones RBBP4/7, the CpG-binding proteins MBD2/3, p66α and/or p66β.
