Table 1.
Gene | Neurodevelopmental Disorders |
---|---|
NuRD Subunits | |
CHD3 | Craniofacial defects, developmental delay, language deficits (Snijders Blok–Campeau syndrome) [50] |
CHD4 | Developmental delay, speech and motor delay, cognitive impairment (Sifrim–Hitz–Weiss syndrome) [51,52] |
CHD5 | Language deficits, intellectual disability, epilepsy, behavioural disorder (Parenti–Mignot neurodevelopmental syndrome) [53] |
GATAD2B | Motor disability, intellectual disability, language deficits, developmental delay, craniofacial abnormalities (GATAD2B-associated neurodevelopmental disorder) [54] |
MBD3 | Non-verbal ASD [55,56] |
Other CHDs | |
CHD2 | Epilepsy, neurobehavioural disorders, intellectual disability [57,58] |
CHD7 | Intellectual disability, hearing and visual impairments, developmental delay, self-injurious behaviour, sleep problems (CHARGE syndrome) [59,60,61] |
CHD8 | Developmental delay, ASD, behavioural disorder, musculoskeletal defects (Intellectual developmental disorder with autism and macrocephaly, IDDAM) [62,63,64] |