Table 1.
Figure | Species | Group | Antigen Dose (μg) |
Adjuvant Dose (μg) |
MP Dose (mg) |
---|---|---|---|---|---|
2 | Mouse | PBS | - | - | - |
HA-PR8 + Sol cGAMP | 1 | 0.2 | - | ||
HA-PR8 + Coaxial cGAMP MPs | 1 | 0.2 | 0.020 | ||
HA-PR8 + Monoaxial cGAMP MPs | 1 | 0.2 | 0.020 | ||
3 | Ferret | PBS | - | - | - |
Fluarix Quadrivalent | 15 | - | - | ||
HA-Cali + Sol cGAMP | 15 | 15 | - | ||
HA-Cali + Monoaxial cGAMP MPs | 15 | 15 | 1.5 | ||
4–5 | Ferret | PBS | - | - | - |
HA-Cali + AddaVax (1X) | 15 | 9.75 mg | - | ||
HA-Cali + Monoaxial cGAMP MPs (Prime) | 15 | 15 μg | 1.5 | ||
HA-Cali + Monoaxial cGAMP MPs (Boost) | 15 | 15 μg | 1.5 |