Joint survival analysis for demographic and diagnostic cohorts: both PEI and the screening panel were prognostic factors. Abbreviations: CI, confidence interval; ECOG-PS, Eastern Cooperative Oncology Group Performance Status; mHR, multivariable hazard ratio; NET, neuroendocrine tumour; PDAC, pancreatic ductal adenocarcinoma; PEI, pancreatic exocrine insufficiency; uHR, univariate hazard ratio. (A) Kaplan-Meier curve for joint demographic and diagnostic cohorts comparing PEI vs. no PEI. (B) Kaplan-Meier cure for joint demographic and diagnostic cohorts comparing Low/Medium risk screening panel vs. High-risk screening panel (C) Overall survival analysis adjusting for other prognostic factors.