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Autophagy is a self-eating mechanism occurring in cells. (A) Different steps in the autophagy pathway. Cargos are first engulfed by autophagosomes, which then fuse with lysosomes. Lysosomal enzymes degrade the cargo resulting in the recycling of the cargo’s building blocks. (B) Selective autophagy. Autophagy can selectively target and degrade specific cargo using different receptor proteins.
