Table 3.
Characteristics of the PRF-related genes.
| PRF-Related Gene | Imaging Feature |
Subtype Specific | Pathway | Module | Correlation Coefficient | p |
|---|---|---|---|---|---|---|
| IRS1 | PRF1 | FIFS1 | Positive Regulation of Cellular Carbohydrate Metabolic Process | Darkorange | 0.534 | 0.003 |
| TBX21 | PRF2 | FIFS1 | T Cell Differentiation Involved in Immune Response | Green | 0.592 | 0.001 |
| CCR7 | PRF3 | FIFS1 | Regulation of JNK Cascade | Green | 0.679 | <0.001 |
| SLAMF6 | PRF4 | FIFS1 | CD4 Positive or CD8 Positive Alpha Beta T Cell Lineage Commitment | Green | 0.611 | 0.001 |
| IL6ST | PRF5 | FIFS1 | JAK-SKAT Signaling Pathway | Green | 0.556 | 0.002 |
| SLAMF6 | PRF6 | FIFS1 | T Helper 17 Cell Differentiation | Green | 0.595 | 0.001 |
| NFIL3 | PRF7 | FIFS1 | Natural Killer Cell Differentiation | Green | 0.577 | 0.001 |
| SPN | PRF8 | FIFS1 | CD4 Positive or CD8 Positive Alpha Beta T Cell Lineage Commitment | Green | 0.518 | 0.004 |
| PRKCQ | PRF9 | FIFS1 | Positive Regulation of Interleukin 17 Production | Green | 0.581 | 0.001 |
| LY9 | PRF10 | FIFS1 | Positive Regulation of Interleukin 17 Production | Green | 0.54 | 0.003 |
| CDC26 | PRF11 | FIFS2 | Anaphase Promoting Complex | Yellow | 0.578 | 0.001 |
| UBE2S | PRF12 | FIFS2 | Regulation of Ubiquitin Protein Ligase Activity | Yellow | 0.662 | <0.001 |
| BAG2 | PRF13 | FIFS2 | Regulation of Ubiquitin Protein Ligase Activity | Yellow | 0.601 | 0.001 |
| UBE2S | PRF14 | FIFS2 | Positive Regulation of Ubiquitin Protein Transferase Activity | Yellow | 0.527 | 0.004 |
| UBE2S | PRF15 | FIFS2 | Regulation of Ubiquitin Protein Ligase Activity | Yellow | 0.623 | <0.001 |
| MAD2L1BP | PRF16 | FIFS2 | Regulation of Mitotic Cell Cycle Spindle Assembly Checkpoint | Yellow | 0.539 | 0.003 |
| SIRT2 | PRF17 | FIFS2 | Positive Regulation of Meiotic Cell Cycle | Yellow | 0.486 | 0.008 |
| SIRT2 | PRF18 | FIFS2 | Regulation of Meiotic Nuclear Division | Yellow | 0.584 | 0.001 |