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The cut-off value of TMB in advanced gastric cancer.
| Clinical Trial | Detection Method | Numbers of Patients | Cut-Off Value | TMB-H (%) |
|---|---|---|---|---|
| NCT0291543 | NK | 54 | ≥12 muts/Mb | 22% |
| KEYNOTE-601 | WES | 420 | ≥175 muts/Exons | 18% |
| KEYNOTE-601 | FoudationOneCDx | 204 | ≥10 muts/Mb | 17% |
| KEYNOTE-602 | FoudationOneCDx | 306 | ≥10 muts/Mb | 16% |
WES, whole-exome sequencing.
