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Antiviral activity of clinically relevant warhead compounds. HCMV AD169-GFP-infected HFFs were treated with compounds to analyze their antiviral activity via quantitation of the GFP reporter signal at 7 d p.i. In parallel, cell viability was assessed using Neutral Red staining of uninfected, compound-treated cells. Mean values ± SDs are given; EC50, CC50 and SI values are indicated below the curves. Hit compounds are marked as underlined in bold.
