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. 2023 Apr 7;13(4):632. doi: 10.3390/brainsci13040632

Figure 5.

Figure 5

EGCG upregulates IL-3, IL-11, and CSF2. PCR array analysis of BV-2 cells shows that EGCG 150 µM + LPS (1 µg/mL) significantly increased mRNA expression of IL-3 (A), IL-11 (B), and CSF2 (C) compared to LPS (1 µg/mL). LPS (1 µg/mL) showed a non-significant increase when compared to EGCG 150 µM with LPS (1 µg/mL). The controls (untreated cells and EGCG 150 µM alone) displayed reduced mRNA expression when compared to LPS and EGCG 150 µM with LPS (1 µg/mL). Values represent the mean ± SD, *** p ≤ 0.001, and **** p ≤ 0.0001 vs. LPS.