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. 2023 Apr 7;15(8):2198. doi: 10.3390/cancers15082198

Figure 12.

Figure 12

Effect of AR-activation on MMP and TIMP levels in the SASP. Continuous activation of ARs in androgen-responsive 84E7 cells shows a significant decrease in MMP-1, -3, and -10 and a moderate increase in inhibitors TIMP-1 and TIMP-2 (* p-value < 0.05, ** p-value < 0.005, *** p-value < 0.0005).