Table 1.
Clinical characteristics of 32 patients with DGF who underwent 2 or more biopsies within the first 60 days after kidney transplantation
| Characteristic | Value |
|---|---|
| Demographics | |
| Age, mean ± SD, years | 50±18 |
| Gender – male, n (%) | 17 (53) |
| Prior kidney transplant, n (%) | 10 (31) |
| Dialysis duration, mean ± SD, months | 60±69 |
| Weight, mean ± SD, kg | 72±19 |
| Height, mean ± SD, m | 1.63±0.09 |
| BMI, mean ± SD, kg/m2 | 28±6 |
|
| |
| Graft | |
| Cold ischemia time, mean ± SD, h | 10±7 |
| Cadaveric graft, n (%) | 22 (69) |
| Donor gender – male, n (%) | 13 (41) |
| Donor age, mean ± SD, years | 52±15 |
| PRA I, mean ± SD, % | 16±25 |
| PRA II, mean ± SD, % | 14±28 |
| PRA >50%, n (%) | 5 (16) |
|
| |
| Induction | |
| Basiliximab, n (%) | 10 (31) |
| Antithymocyte globulin, n (%) | 22 (69) |
| HLA mismatch (A, B, DR), mean ± SD | 3.7±2.0 |
|
| |
| ESRD etiology | |
| Unknown, n (%) | 9 (28.1) |
| Diabetes, n (%) | 7 (21.9) |
| FSGS, n (%) | 6 (18.8) |
| Other – hypertension, IgA, lupus, | |
| nephronophthisis, n (%) | 10 (31.3) |
| DGF cases, n | 17* |
| DGF duration, mean ± SD, days | 28±13 |
| PNF, n (%) | 15 (46.9) |
| Time to first biopsy, mean ± SD, days | 8.5±5.4 |
| Time to second biopsy, mean ± SD, days | 23.4±12.6 |
DGF, delayed graft function; ESRD, end-stage renal disease; FSGS, focal segmental glomerulosclerosis; PRA, panel-reactive anti-body; BMI, body mass index. * Four patients in whom the graft partially functioned immediately but with some compromise that warranted biopsy study were added to the GDF group for comparison with patients with PNF (Table 2).