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. 2023 Apr 21;15(8):2405. doi: 10.3390/cancers15082405

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Screening of DEGs related to the defense response. (A) Volcano plot illustrating the DEGs in osteosarcoma and normal groups with the threshold set at |logFC| ≥ 1 and adj-p ≤ 0.05. (B) DEGs are significantly enriched in the GOBP_DEFENSE_RESPONSE pathway. (C) Trend in the number of studies on GOBP_DEFENSE_RESPONSE pathways in recent years. (D) DRGs obtained by taking the intersection of DEGs and GOBP_DEFENSE_RESPONSE pathway genes. (E) Heatmap showing the expression of DRGs in osteosarcoma samples and normal samples.