Figure 6.
The effects of RNA editing events on genes in other datasets. (A,B) In blood samples of PD patients from PPMI and GEO (GSE165082), the RNA editing event at Chr1:160998027 shows significant associations with F11R. (C–E) In healthy blood samples, the three RNA editing events discussed in detail also show significant associations with corresponding genes. (F) In temporal cortex (TCX) regions of AD patients, the RNA editing event at Chr2:37104057 is significantly associated with EIF2AK2 and MCL1. (G,H) In cerebellum (CER) and dorsolateral prefrontal cortex (DLPFC) regions of AD patients, the RNA editing event (Chr9:63819627) in the seed region of miR-4477b may dysregulate AGO2 and AIMP2.
