Figure 6.
A combination of QUE, SFN, and OXP suppressed HCT116 xenograft tumor growth. QUE suppressed the tumor growth of HCT116 cells in vivo. The xenograft tumors were established by subcutaneously transplanting 3 × 106 HCT116 cells to BALB/c mice. The xenograft tumor-bearing mice were treated with QUE (50 mg/kg BW), OXP (10 mg/kg BW), SFN (5 mg/kg BW), and their combinations as designated by intraperitoneal injection. Tumor growth in xenografts was measured three times per week. Error bars represent mean ± SD from four tumor samples (n = 4). A significant difference is indicated by asterisk, *, and hashtag, #, compared with vehicle and SFN-treated group (p < 0.05, Student’s unpaired t-test).