Fig 3. Interpretation of two examples of personalized predictions of the number of MII oocytes.

The effect of all features used in the clinical-genetic predictive model on the predictions of the number of MII oocytes was estimated retrospectively for (A) Patient 1 and (B) Patient 2. The x-axis shows the number of MII oocytes, and the y-axis shows the included features. The arrows indicate the contribution of each feature to the final prediction f(x) obtained for a patient; red and blue indicate an increase or decrease in the predicted number of MII oocytes by the factor, respectively. A detailed interpretation of both cases is provided in the text. AFC—antral follicle count; AMH—anti-Müllerian hormone; nan—not a number; PCOS—polycystic ovary syndrome.