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. 2023 Apr 27;19(4):e1011020. doi: 10.1371/journal.pcbi.1011020

Table 2. Genetic features identified as important for the prediction of the number of MII oocytes after ovarian stimulation.

Genetic feature Methoda Gene dbSNP IDb Sequence variant Allele frequencyc
IV-CA CA LHCGR rs11887058 NC_000002.12:g.48729336C>T T = 0.428
PRLR rs112461 NC_000005.10:g.35063190A>T T = 0.242
ESR1 rs2207396 NC_000006.12:g.152061247G>A A = 0.356
IV8-6 SOM GDF9 rs11739194 NC_000005.10:g.132865538T>C C = 0.515
rs17166294 NC_000005.10:g.132866205T>C C = 0.288
LHCGR rs11887058 NC_000002.12:g.48729336C>T T = 0.428
FSHB rs676349 NC_000011.10:g.30234435A>G G = 0.523
ESR1 rs2273207 NC_000006.12:g.152061190A>G G = 0.117
ESR2 rs928554 NC_000014.9:g.64227477C>T T = 0.731
IV22-2 Haplotype FSHR rs80111020 NC_000002.12:g.48962060 = A = 0.909
rs6166 NC_000002.12:g.48962782C>T T = 0.701
IV41-8 Haplotype PRLR rs387032 NC_000005.10:g.35061629 = T = 0.845
rs401694 NC_000005.10:g.35062516 = C = 0.765
rs112461 NC_000005.10:g.35063190 = A = 0.758
rs1057828 NC_000005.10:g.35064413 = C = 0.939
rs56251626 NC_000005.10:g.35064922 = C = 0.936
rs62355478 NC_000005.10:g.35065548 = C = 0.992
rs78373811 NC_000005.10:g.35068146 = G = 0.913
rs186609463 NC_000005.10:g.35069864 = G = 0.985
IV16-3 Haplotype GDF9 rs75061517 NC_000005.10:g.132866082 = T = 0.689
rs17166294 NC_000005.10:g.132866205 = T = 0.712
rs30177 NC_000005.10:g.132866719C>G G = 0.924

a—features were determined using correspondence analysis (CA), self-organizing map (SOM) algorithm, and haplotype analysis followed by a reduction of the number of variants

b—dbSNP Reference SNP number according to the National Center for Biotechnology Information (NCBI) dbSNP database (https://www.ncbi.nlm.nih.gov/snp/, accessed: 2022-04-05)

c—allele frequencies were calculated for Group 2 consisting of 264 women.

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