Triage Strategies
Dual staining	Positive: At least one observed p16/Ki-67 dual stained epithelial cell Negative: No p16/Ki-67 dual stained epithelial cells observed
Cytology	Positive: ASC-US or worse cytology Negative: NILM cytology
HPV 16/18	Positive: HPV genotype 16 and/or 18 present, possibly also 12 other high risk genotypes Negative: No HPV genotype16/18 present i.e., only 12 other high risk genotypes
Dual staining and HPV 16/18	Positive: Positive dual staining and positive HPV 16/18 Negative: Negative dual staining and/or negative HPV 16/18
Cytology and HPV 16/18	Positive: Positive cytology and positive HPV 16/18 Negative: Negative cytology and/or negative HPV 16/18
Dual staining and/or HPV 16/18	Positive: Positive dual staining and/or positive HPV 16/18 Negative: Negative dual staining and negative HPV 16/18
Cytology and/or HPV 16/18	Positive: Positive cytology and/or positive HPV 16/18 Negative: Negative cytology and negative HPV 16/18
Outcomes
CIN2+	Positive: CIN2 or worse histology; Negative: CIN1 or less histology or no histology but negative follow-up HPV test
CIN3+	Positive: CIN3 or worse histology; Negative: CIN1 or less histology or no histology but negative follow-up HPV test