Table 2.
Baseline laboratory findings of studied COVID-19 patients.
| Parameters | Control | Moderate COVID-19 |
Severe COVID-19 |
Critical COVID-19 |
p-Value |
|---|---|---|---|---|---|
| HB (g/dL) | 12.9 ± 2 | 13 ±1.2 | 13.17 ± 0.9 | 12.41 ± 1.7 | 0.91 |
| PLT (×103/µL) | 230.9 ± 71.5 | 215.3 ± 76.8 | 239.5 ± 81.7 | 233.8 ± 102.4 | 0.519 |
| TLC (×103/µL) | 6.9 ± 1.7 | 7.7 ± 4.2 | 8.1 ± 3.4 | 12.8 ± 7.4 | 0.001 * |
| Neutrophils (%) | 74.5 ± 9.4 | 76.8 ± 13.5 | 77.2 ± 12.7 | 83 ± 10.6 | 0.001 * |
| Lymphocyte (%) | 19.3 ± 8.2 | 15.4 ± 10.6 | 16.2 ± 10.4 | 11.5 ± 8.5 | 0.001 * |
| NLR | 7.2 ± 4.1 | 7.6 ± 5.4 | 6.6 ± 3.4 | 13.9 ± 12.6 | 0.001 * |
| ALB (g/dL) | 3.7 ± 0.3 | 3.5 ± 0.3 | 3.4 ± 0.4 | 3.2 ± 0.5 | 0.001 * |
| Calcium (mg/dL) | 8.7 ± 0.5 | 8.7 ± 0.5 | 8.6 ± 0.5 | 7.9 ± 1.6 | 0.001 * |
| Sodium (mEq/L) | 137.1 ± 3.1 | 136.6 ± 3 | 136 ± 2.1 | 138.9 ± 5.7 | 0.047 * |
| Potassium (mEq/L) | 3.9 ± 0.4 | 3.6 ± 0.4 | 3.7 ± 0.5 | 3.9 ± 0.7 | 0.078 * |
| Indirect bilirubin (µg/dL) | 0.5 ± 0.2 | 0.6 ± 0.5 | 0.5 ± 0.3 | 0.7 ± 0.3 | 0.006 * |
| Direct bilirubin (µg/dL) | 0.2 ± 0.09 | 0.3 ± 0.2 | 0.2 ± 0.2 | 0.3 ± 0.3 | 0.094 |
| PT (seconds) | 13.7 ± 1.4 | 13.5 ± 1.1 | 14.1 ± 2.2 | 18.7 ± 9.9 | 0.001 * |
| PTT (seconds) | 34.4 ± 6.1 | 35.2 ± 6 | 38.8 ± 9.4 | 37.7 ± 8.7 | 0.015 * |
| Creatinine (mg/dL) | 0.6 ± 0.1 | 0.7 ± 0.2 | 0.6 ± 0.1 | 0.6 ± 0.2 | 0.213 |
| eGFR (ml/min/1.73 m2) | 106.6 ± 16.5 | 108.8 ± 19.6 | 103.6 ± 11.2 | 107.3 ± 17.4 | 0.247 |
| LDH (IU/L) | 168.7 ± 22.3 | 316.1 ± 101.2 | 355 ± 104.2 | 348.2 ± 116.7 | 0.001 * |
| CRP (mg/dL) | 4.9 ± 1.5 | 89 ± 32.8 | 74.7 ± 35.7 | 91.8 ± 49.8 | 0.001 * |
| O2 Saturation (%) | 97.5 ± 0.9 | 94.9 ± 1.2 | 91.8 ± 1.7 | 87.4 ± 3.9 | 0.001 * |
Data are presented as mean and standard deviation. One-way ANOVA was used to calculate the p-values. * Significant at p < 0.05. HB: hemoglobin, PLT: platelet, TLC: total leucocytic count, NLR: neutrophils to lymphocyte ratio, ALB: albumin, PT: prothrombin time, PTT: partial thromboplastin time, eGFR: estimated glomerular filtration rate, LDH: lactate dehydrogenase, and CRP: C-reactive protein.