Skip to main content
. 2023 Apr 14;24(8):7293. doi: 10.3390/ijms24087293
ABH2 Alkylated DNA repair protein alkB homolog 2
ABH3 Alkylated DNA repair protein alkB homolog 3
AML Acute myeloid leukaemia
APE1 AP-endonuclease 1
BER Base excision repair
BRCA Breast cancer susceptibility protein
DDB2 DNA damage-binding protein 2
DDR DNA damage response
DNA Deoxyribonucleic acid
DNA-PKcs DNA-dependent protein kinase catalytic subunit
DSB Double stand break
EOC Epithelial ovarian cancer
FDA Food and Drug Administration
FEN1 Flap-endonuclease 1
GG-NER Global-genome NER
gLOH Genomic patterns of loss of heterozygosity
HNPCC Hereditary nonpolyposis colorectal cancer
HR Homologous recombination
ICL Interstrand crosslink
IDL Insertion/deletion loop
IR Ionizing radiation
MDS Myelodysplastic syndrome
MGMT Methylguanine methyltransferase
MLH1 MutL homolog 1
MMC Mitomycin C
MMR Mismatch repair
MRN Mre11-Rad50-Nbs1
MSH2 MutS homolog 2
MSH3 MutS homolog 3
NER Nucleotide excision repair
NGS Next-generation sequencing
NHEJ Non-homologous end joining
OS Overall survival
PARP Poly(ADP-ribose) polymerase
PARPi Poly(ADP-ribose) polymerase inhibitor
PCNA Proliferating cell nuclear antigen
PD1 Programmed cell death protein 1
PD-L1 Programmed cell death ligand 1
PFS Progression-free survival
PLD Pegylated liposomal doxorubicin
PMS2 Postmeiotic segregation increased 2
PNKP Polynucleotide kinase/phosphatase
Polβ Polymerase beta
ROS Reactive oxygen species
RPA Replication protein A
SDSA Synthesis-dependent strand annealing
SSBR Single-strand break repair
TC-NER Transcription-coupled NER
UV Ultraviolet
XRCC1 X-ray cross-complementing group 1 protein