Table 2.
Validation of growth performance of iBB1018 under various carbon source and production scenarios. Constraints used to feed the model are underlined.
| Carbon Source Substrate a Uptake (mmol g−1 h−1) |
In Vivo Riboflavin Secretion (mmol g−1 h−1) |
In Vivo Growth Rate (h−1) |
In Silico Growth Rate (h−1) |
|---|---|---|---|
| vglc = 1.55; vcit = 0.5 | 0.0173 | 0.10 | 0.12 |
| vglc = 1.55; vglcn_D = 0.6 | 0.0258 | 0.12 | 0.13 |
| vglc = 1.7 | 0.0181 | 0.10 | 0.10 |
| vglc = 3.2 | 0.0210 | 0.20 | 0.24 |
| vglc = 4.7 | 0.0231 | 0.30 | 0.39 |
| vglc = 6.2 | 0.0255 | 0.40 | 0.54 |
a glc: D-glucose; cit: citrate; glcn_D: D-gluconate.