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. 2023 Apr 13;24(8):7228. doi: 10.3390/ijms24087228

Table 1.

Examples of recommendations regarding aluminium exposure limits.

Source of
Exposure to Al
Exposure to Al Limits Comments Organization, References
Occupational exposure limits Al alkyls, NOS—PEL of 2 mg/m3;
Al soluble salts—PEL of 2 mg/m3;
Al metal and oxide (total dust)—PEL of 10 mg/m3;
Al metal and oxide (respiratory fraction)—PEL of 5 mg/m3;
Al pyro powders—PEL of 5 mg/m3;
Al welding fumes—PEL of 5 mg/m3;
Al stearate—PEL of 10 mg/m3;
Al distearate—PEL of 10 mg/m3;
Al tristearate—PEL of 10 mg/m3.
8-h TWA was used in this document. Cal/OSHA [14,15]
Al (total dust)—PEL of 15 mg/m3
Al (respirable fraction)—PEL of 5 mg/m3
- OSHA [14]
Al (total dust)—REL of 10 mg/m3;
Al (respiratory fraction)—REL of 5 mg/m3;
Up-to-10-h TWA was used in this document. NIOSH [14,16]
Oral exposure TWI of 1 mg/kg bw/week EFSA [17]
NOAEL of 30 mg/kg bw/day;
LOAEL of 50–75 mg/kg bw/day;
PTWI of 2 mg/kg bw.
Major contributors to the total oral Al exposure were cereals and cereal-based products, accounting for 20–90% of total dietary Al exposure. WHO [18]
Drinking water For small water treatment facilities—0.2 mg/L
For large water treatment facilities—0.1 mg/L
- WHO [19]
0.05 to 0.2 mg/L Al level belongs to secondary standards, regarding substances that could cause “cosmetic effects (such as skin or tooth discoloration) or aesthetic effects (such as taste, odor, or color)”. EPA [20]
Freshwater (regarding aquatic life) CMC of 1–4800 μg/L
CCC of 0.63–3200 μg/L
Wide range of Al CMC and CCC is caused by significant dependence of Al–bioavailability and certain factors (mostly important ones are total hardness, pH, and dissolved organic carbon). EPA [21]
Toys “Dry, brittle, powder-like or pliable toy material”—2250 mg/kg;
“Liquid or sticky toy material”—560 mg/kg;
“Scraped-off toy material”—28130 mg/kg.
SCHEER suggests that additional exposure from toys should be minimized due to high exposure to Al from other sources. SCHEER [22]

Abbreviations: Al—aluminium; bw—body weight; Cal/OSHA—California’s Division of Occupational Safety and Health; CCC—criteria chronic concentration; CMC—criteria maximum concentration; EFSA—European Food Safety Authority; EPA—Environmental Protection Agency; LOAEL—lowest-observed-adverse-effect level; NIOSH—The National Institute for Occupational Safety and Health; NOAEL—no-observed-adverse-effect level; NOS—not otherwise specified; OSHA—Occupational Safety and Health Administration; PEL—permissible exposure limit; PTWI—provisional tolerable weekly intake; REL—recommended exposure limit; SCHEER—Scientific Committee on Health, Environmental and Emerging Risks; TWA—time-weighted average; TWI—tolerable weekly intake; WHO—World Health Organization.