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. 2023 Apr 11;24(8):7073. doi: 10.3390/ijms24087073

Table 1.

Analysis of synergy for the combinations of PPRHs and trastuzumab in SKBR-3 cells.

Dose HpI4 (nM) Dose HpI6
(nM)
Dose TZ
(µg/mL)
CI Media Description
30 - 100 0.76 Moderate synergism
50 - 100 0.72 Moderate synergism
100 - 100 0.51 Synergism
- 30 100 0.66 Synergism
- 50 100 0.60 Synergism
- 100 100 0.93 Nearly additive

The concentrations of PPRHs and antibodies, the calculated combination index (CI), and the description of the resulting effect are shown.