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. 2023 Apr 19;24(8):7511. doi: 10.3390/ijms24087511

Figure 2.

Figure 2

Effects of Y151S mutation on agonist potency on the receptor Nlα1Y151S/β2. (A) Representative currents elicited by imidacloprid and cycloxaprid on wildtype receptor Nlα1/β2 (left) and mutant receptor Nlα1Y151S/β2 (right). The concentrations (µM) were provided following drug name, imidacloprid (Imi) and cycloxaprid (Cyc). (B) Concentration-response curve for inward currents induced by imidacloprid and cycloxaprid (n = 6–12). The currents were normalized to the maximum currents elicited by 1000 µM imidacloprid on the wildtype receptor Nlα1/β2. Data were presented as mean ± SEM.