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. 2023 Apr 11;24(8):7088. doi: 10.3390/ijms24087088

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Differentially expressed ncRNAs profiles in plasma exosome fraction of SLE patients with or without LN compared to control subjects. (A) Venn diagram shows the overlap among biological fractions. (B) Diverging bar charts show the fold-change expression of the exosomal non-coding RNAs signature in both groups: upregulated are in green and downregulated in red. Common NcRNAs in both signatures are in bold. logFC: logarithm 2 base fold-change; (C) Proportions of DE ncRNA biotypes in plasma exosomes from SLE patients with LN or without (nLN). Exo-P: plasma exosomes; LN, lupus nephritis; lncRNA: long non-coding RNA; miRNA: microRNA; piRNA: PIWI-interacting RNA; nLN: non lupus nephritis.