Table 1. Demographic, clinical and laboratory characteristics of the patients according to the group of membranoproliferative glomerulonephritis.
| Total (N=53) | Primary (N=36) | Secondary (N=17) | P | |
|---|---|---|---|---|
| Male gender, n (%) | 26 (49.1) | 15 (41.7) | 11 (64.7) | 0.117a |
| Age (years) | 53 ± 15.1 | 38.1 (±16.3) | 40.4 (±12.4) | 0.675b |
| Hypertension, n (%) | 45 (84.9) | 30 (83.3) | 15 (88.2) | >0.999c |
| Edema, n (%) | 47 (88.7) | 31 (86.1) | 16 (94.1) | 0.651c |
| Anemia, n (%) | 45 (84.9) | 29 (80.6) | 16 (94.1) | 0.412c |
| Nephrotic syndrome, n (%) | 15 (33) | 10 (32.3) | 5 (35.7) | >0.999a |
| Initial SAlb (g/dL) | 2.8 ± 0.7 | 2.8(±0.7) | 2.8 (±0.7) | 0.740d |
| Hematuria, n (%) | 50 (94.3) | 33 (91.7) | 17 (100) | 0.525c |
| Initial 24hP (g/24h) | 5.2 (±4.6) | 5.5 (±5.2) | 4.5 (±2.9) | 0.935b |
| Initial SCr (mg/dL) | 1.5 (±1.0) | 1.4 (±0.9) | 1.7 (±1.1) | 0.360b |
| eGFR (mL/min/1.73m 2 ) | 66.6 (±36.3) | 69.2 (±36.9) | 61.2 (±35.4) | 0.293b |
| Low serum C3 level | 24 (49.0) | 16 (48.5)* | 8 (50)** | 0.921a |
| Low serum C4 level | 23 (46.9) | 13 (39.4)* | 10 (62.5)** | 0.129a |
| Final SAlb (g/dL) | 3.7(±0.6) | 3.6(±0.6) | 3.8 (±0.6) | 0.218d |
| Final 24hP (g/24h) | 3.2(±3.8) | 3.6 (±3.8) | 2.4 (±3.7) | 0.257b |
| Final SCr (mg/dL) | 2.4 (±2.3) | 2.6 (±2.4) | 2.0 (±1.9) | 0.435b |
| eGFR < 15mL/min | 7 (13.2) | 5 (13.9%) | 2 (11.8%) | >0.999c |
| SCr 2x initial level | 15 (28.3) | 13 (36.1%) | 2 (11.8%) | 0.103c |
| Follow up time | 6.3 (±7.4) | 6.3 (±5.5) | 6.2 (±10.6) | 0.182b |
Values for continuous variables are expressed as mean ± SD. aPearson's Chi-Square, bMann-Whitney, cFisher's exact, dStudent’s t-test for independent samples. SAlb: serum albumin; SCr: serum creatinine; 24hP: 24-hour proteinuria; eGFR: estimated glomerular filtration rate (CKD-EPI).
*
33 patients analyzed;
**
16 patients analyzed.