Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 27;2023(4):rjad225. doi: 10.1093/jscr/rjad225

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

The specimen shows severe diffuse necrotizing colitis (A). Histology reveals extensive ulcerous colitis with deep-reaching ulcers and mural necrosis (B1 and C1). Multinucleated epithelial cells with eosinophilic inclusions can be discerned (insert B1). Immunohistochemistry for human HSV confirms a widespread infection of the mucosa and the mural part of the colonic wall (B2 and C2). Epithelial cells, as well as stromal cells, are positive (insert B2). B1 and C1: Hematoxylin and Eosin; C1 and C2: Immunohistochemistry for HSV (Chromogen: Fast Red).