Table 1.

Characteristics of newly identified studies for ‘Advanced Life Support’, and ‘Helping Babies Breathe Training’ (characteristics of all included studies are listed in Appendix 1).

Advanced life support studies
Author Year Country	Study design	Setting	Number of patients	Outcome measures	Results
Pareek15 2018 India	Retrospective cohort study, pre- and post- AHA ACLS	750 bed tertiary care hospital	632 – 294 pre ACLS; 338 post ACLS; no data on age or sex	ROSC; Survival to hospital discharge	• ROSC increased from 19.7% to 30.1% (p = 0.003)
					• Significant increase in survival to hospital discharge post-BLS/ACLS training (p < 0.0001)
Helping babies breathe studies
Innerdal17 2020 Mali	Pre-post training	Local district hospital	9769: 3125 pre-training; 6644 post-training	Fresh stillbirth rate, 1-day neonatal mortality, perinatal mortality	• Perinatal mortality rate (PMR) decreased from 21.7/1000 births to 6.0/1000 live births; RR 0.27, (95% CI 0.19–0.41; p < 0.0001).
					• 1-day neonatal mortality rate decreased from 6.3/1000 to 0.8/1000 live births; RR 0.12 (95% CI 0.05–0.33; p = 0.0006).
					• Fresh stillbirth rate decreased from 15.7/1000 to 5.3/1000, RR 0.33 (95% CI 0.22–0.52; p < 0.0001)
Patterson16 2021 Democratic Republic of Congo	Pre-post training	Three health facilities	24977: 13,840 pre-training; 11,137 post-training	Total stillbirth, fresh stillbirth, macerated stillbirth, neonatal death before discharge, perinatal death	• No change in total stillbirths following resuscitation training and continuous electronic HR monitoring of non-breathing newborns (aRR 1.15 [0.95, 1.39]).
					• Increased rate of macerated stillbirth (aRR 1.58 [1.24, 2.02]), death before discharge (aRR 3.31 [2.41,4.54]), and perinatal death (aRR 1.61 [1.38, 1.89]) during the intervention period.

BLS- Basic Life Support; ACLS- Advanced Cardiac Life Support; HBB – Helping Babies Breath.