Table 5.
GRADE Summary of findings table for ‘Advanced life support’.
| No of patients |
Effect | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | ACLS/ ALS | No ACLS/ ALS | Relative (95% CI) | Certainty | Importance |
| ROSC | |||||||||||
| 7 | Observational studies | seriousa | seriousb | seriousc | seriousd | none | 480/ 1211 (39.6%) | 261/ 882 (29.6%) | OR 1.66 (1.24 to 2.21) |  |
CRITICAL |
| Survival to discharge and 30 days | |||||||||||
| 8 | Observational studies | seriousa | seriousb | seriousc | seriousd | none | 309/ 995 (31.1%) | 111/ 672 (16.5%) | OR 2.48 (1.21 to 5.09) | |
CRITICAL |
| 1 year survival | |||||||||||
| 2 | Observational studies | seriousa | seriousb | seriousc | seriousd | none | 51/ 262 (19.5%) | 31/ 193 (16.1%) | OR 3.61 (0.11 to 119.42) | |
CRITICAL |
a
Mixture of serious and low risk of bias studies.
b
Some studies showed significant improvement, and some showed no improvement.
c
Differences in patient type, hospital type, provider type and team composition, and nature of intervention.
d
Absence of confidence intervals.