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. 2023 Mar 29;26(4):106522. doi: 10.1016/j.isci.2023.106522

Figure 1.

Figure 1

ELISA for identification of H. suis and H. pylori infection

Serum specimens (n = 101) were divided into four groups: an H. suis-infection group (n = 20), an H. pylori-infection group (n = 17), a group with eradication of H. pylori infection (n = 20), and a group with neither H. suis nor H. pylori infection (n = 44).

(A) ELISA for detecting H. suis infection. ∗∗∗p< 0.0001, the H. suis infection group vs. the H. pylori infection, the post-eradication of H. pylori infection, or the non-infection group. The red dotted line indicates the cut-off value (1.0). The bar represents the mean with SD.

(B) ROC curve constructed from the H. suis-infection group vs. the H. suis non-infection groups, which consisted of the H. pylori infection, the post-eradication of H. pylori infection, and the non-infection groups. The red slanted line is the reference line. The area under the ROC curve (AUC): 0.96 ± 0.02; 95% CI: 0.93 to 1.00; p< 0.0001.

(C) ELISA for detecting H. pylori infection. ∗∗∗∗p< 0.0001, the H. pylori infection group vs. the H. suis infection or non-infection group. #p> 0.05, the H. pylori infection group vs. the post-eradication of H. pylori infection group. The blue dotted line indicates the cut-off value (0.8). The bar represents the mean with SD.

(D) ROC curve constructed from the H. pylori infection group vs. the H. pylori non-infection groups, including the H. suis infection and the non-infection groups. The red slanted line is the reference line. AUC: 0.92 ± 0.03; 95% CI: 0.86 to 0.98; p< 0.0001.