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. 2023 Apr 27;13:6866. doi: 10.1038/s41598-023-33922-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Exemplary dataset in native space displaying the four used MRI parameters in coronal view (FWF: free water fraction, ODI: orientation dispersion index corrected for FWF, NDI: neurite density index corrected for FWF, R2*: effective transverse relaxation rate), as well as the ODI image zoomed in on the hypothalamus area and overlaid with the hypothalamus masks after correction for confounding white matter (beige: superior, blue: intermediate, brown: posterior subunits). The inferior subunit is not visible on this slice.