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. 2023 Apr 27;13:6866. doi: 10.1038/s41598-023-33922-5

Table 3.

Linear mixed effects on hypothalamic microstructure (neurite density index (NDI), orientation dispersion index (ODI), free water fraction (FWF), and effective transverse relaxation rate (R2*)) between subunits (anterior-inferior (A-Inf), anterior–superior (A-sup), intermediate (Int), posterior (Post)) and across age while controlling for sex.

NDI ODI FWF R2*
β (SE) t β (SE) t β (SE) t β (SE) t
Intercept − 0.42 (0.16) − 2.582* − 0.58 (0.17) − 3.464*** 0.84 (0.13) 6.408*** − 0.34 (0.20) − 1.736
Sex (Female) − 0.30 (0.18) − 1.662 − 0.23 (0.18) − 1.326 0.06 (0.15) 0.398 − 0.21 (0.23) − 0.906
Age 0.22 (0.13) 1.681 − 0.31 (0.14) − 2.281* − 0.09 (0.10) − 0.922 0.06 (0.15) 0.366
Subunit (-A-Inf)
A-Sup 0.55 (0.15) 3.561*** 1.01 (0.17) 5.907*** − 1.53 (0.10) − 15.414*** 0.41 (0.16) 2.498*
Int 0.33 (0.15) 2.142* 1.33 (0.17) 7.805*** − 1.79 (0.10) − 18.037*** 0.51 (0.16) 3.154**
Post 1.47 (0.15) 9.520*** 0.50 (0.17) 2.947** − 0.20 (0.10) − 1.989 * 0.92 (0.16) 5.647***
Age × Subunit (-A-Inf)
Age: A-Sup − 0.16 (0.16) − 1.016 0.41 (0.17) 2.404* 0.13 (0.10) 1.272 − 0.29 (0.16) − 1.761
Age: Int − 0.13 (0.16) − 0.827 0.16 (0.17) 0.916 0.10 (0.10) 1.036 − 0.28 (0.16) − 1.730
Age: Post − 0.04 (0.16) − 0.259 0.26 (0.17) 1.498 0.08 (0.10) 0.753 0.04 (0.16) 0.249

*** p < .001, ** p < .01, * p < .05.

Significant values are in [bold].