Table 3.
Top 10 predicted targets of compound 45
| Target | Common name | UniProt ID | Target class |
|---|---|---|---|
| Serine/threonine-protein kinase haspin | HASPIN | Q8TF76 | Kinase |
| Dual-specificity tyrosine-phosphorylation regulated kinase 2 | DYRK2 | Q92630 | Kinase |
| Butyrylcholinesterase | BCHE | P06276 | Hydrolase |
| Acetylcholinesterase | ACHE | P22303 | Hydrolase |
| Dual specificity tyrosine-phosphorylation-regulated kinase 4 | DYRK4 | Q9NR20 | Kinase |
| Dual-specificity tyrosine-phosphorylation regulated kinase 1A | DYRK1A | Q13627 | Kinase |
| Nischarin | NISCH | Q9Y2I1 | Other cytosolic proteins |
| Dual-specificity tyrosine-phosphorylation regulated kinase 3 | DYRK3 | O43781 | Kinase |
| Monoamine oxidase A | MAOA | P21397 | Oxidoreductase |
| Monoamine oxidase B | MAOB | P27338 | Oxidoreductase |