Skip to main content
. Author manuscript; available in PMC: 2023 Oct 6.
Published in final edited form as: N Engl J Med. 2023 Apr 6;388(14):1296–1306. doi: 10.1056/NEJMoa2211934

Figure 4. Antimicrobial Resistance and Culture Positivity in Neisseria gonorrhoeae and Staphylococcus aureus.

Figure 4.

In Panel A, the bar height represents N. gonorrhoeae cultures obtained from participants with lab-confirmed gonorrhea at baseline and for adjudicated gonorrhea end points according to study group during follow-up. Of the gonorrhea diagnoses, 44 of 256 N. gonorrhoeae infections (17.2%) had data available for resistance testing. The dark shading represents high-level tetracycline resistance (minimum inhibitory concentration [MIC], ≥2 μg per milliliter). The light shading represents N. gonorrhoeae without high-level tetracycline resistance. Gonorrhea culture was performed through the Centers for Disease Control and Prevention (CDC) Strengthening the United States Response to Resistant Gonorrhea program, and tetracycline-resistance testing was performed by agar dilution through the CDC Antimicrobial Resistance Laboratory Network. With respect to Panel B, all the participants had oronasopharyngeal swabs obtained at enrollment and at months 6 and 12, which were cultured for S. aureus. The bar height represents the percentage culture-positive for S. aureus, and the dark shading represents specimens with doxycycline resistance by ETEST (MIC, ≥16 μg per milliliter).