TABLE 3.

Characteristics of Children with Severe Recurrent Bacterial Pneumonia at Time of Diagnosis

Characteristic			N = 136
Age (years)	<5	84	61.8%
	5 to <10	41	30.1%
	10 to <15	10	7.4%
	≥15	1	0.7%
	Median (IQR)	4.1	(1.9, 6.3)
Sex	Male	75	55.1%
	Female	61	44.9%
Height-for-age z-score	>−2.0	32	23.5%
	−2.0 to −3.0	22	16.2%
	<−3.0	45	33.1%
	Unknown	37	27.2%
	Median (IQR)	−2.7	(−3.7, −1.7)
Weight-for-age z-score	>−2.0	40	29.4%
	−2.0 to −3.0	30	22.1%
	<−3.0	61	44.9%
	Unknown	5	3.7%
	Median (IQR)	−2.8	(−4.6, −1.7)
Hemoglobin	Normal	52	38.2%
	Mild/moderate anemia	35	25.7%
	Severe anemia	11	8.1%
	Unknown	38	27.9%
Past severe recurrent bacterial pneumonia	No	99	72.8%
	Yes	37	27.2%
Past pulmonary tuberculosis	No	121	89.0%
	Yes	15	11.0%
Past Pneumocystis pneumonia	No	132	97.1%
	Yes	4	2.9%
Past symptomatic lymphoid interstitial pneumonitis	No	130	95.6%
	Yes	6	4.4%
Past chronic HIV-associated lung disease*	No	131	96.3%
	Yes	5	3.7%
Past recurrent severe bacterial infection (excluding pneumonia)	No	134	98.5%
	Yes	2	1.5%
CD4%	≥25%	19	14.0%
	10–24%	37	27.2%
	<10%	43	31.6%
	Unknown	37	27.2%
	Median (IQR)	11.3	(2.9, 23.0)
HIV viral load, copies/ml	Undetectable	9	6.6%
	Detectable	42	30.9%
	Unknown	85	62.5%
	Median (IQR)	25,163	(400, 138,795)
ART regimen	NNRTI-based	122	89.7%
	PI-based	11	8.1%
	Other ART	1	0.7%
	Treatment break	2	1.5%

ART, antiretroviral therapy; IQR, interquartile range; NNRTI, non-nucleoside reverse transcriptase inhibitor; PI, protease inhibitor.

All values are n (%N) unless otherwise specified.

^*including bronchiectasis.