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. 2023 Apr 14;14:1156219. doi: 10.3389/fimmu.2023.1156219

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Copyright © 2023 Jia, Feng, Dooley, Zou and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of ScCD8 genes. (A) Gene synteny analysis of CD8α, the synteny information for human, mouse, chicken, elephant shark, great white shark, zebrafish and small-spotted catshark, and spotted gar genes were obtained from the Ensembl database. (B) Neighbor-joining (N-J) phylogenetic tree of CD8 genes. The tree was constructed using the N-J method within the MEGA-X program with bootstrap values shown next to the branches based on 10,000 bootstrap replications. “◼” indicates ScCD8α (red) and ScCD8β (purple). The accession numbers of protein sequences are provided in Supplementary Table 1 .