Figure 5.

Tumor growth kinetics in wild type and IFNR1^-/- mice: 50,000 B16F10 cells were injected in the right flank of wild type (BL/6) and IFNR1^-/- mice. MIP was administered peritumorally on day 3, 10, 17 post tumor implantation. Tumor growth was measured every 3 days. Control tumor bearing mice were injected PBS instead of MIP. Tumor volume was calculated using the formula (0.5 x large diameter x small diameter²). Data are mean ± SEM values obtained from 8 mice/group. Statistical analysis was performed using two-way ANOVA. (**:p<0.01) Three independent experiments have been repeated.