TABLE 1.
Study population and embryo characteristics. PGT-A was performed by next-generation sequencing (mosaic range defined between 30%–70% aneuploid cells). a Days post-fertilization. b Embryo quality assessed according to guidelines from the Spanish Association for the Study of Biology of Reproduction (ASEBIR).
| Embryo number | Day of biopsya | Gradeb | NGS (% of aneuploid cells in the TE biopsy) | PGT-A diagnosis |
|---|---|---|---|---|
| EU1 (08) | 5 | B | (<30%) | Euploid |
| EU2 (11) | 6 | B | (<30%) | Euploid |
| EU3 (13) | 5 | C | (<30%) | Euploid |
| EU4 (20) | 5 | B | (<30%) | Euploid |
| EU5 (22) | 5 | B | (<30%) | Euploid |
| LM1 (04) | 5 | B | +6 (30%–50%), −7 (30%–50%) | Low-level mosaic |
| LM2 (16) | 6 | C | −22 (30%–50%) | Low-level mosaic |
| LM3 (19) | 5 | B | +4 (30%–50%) | Low-level mosaic |
| LM4 (24) | 5 | C | +8 (30%–50%), −22 (30%–50%) | Low-level mosaic |
| LM5 (26) | 5 | B | +12 (30%–50%), +20 (30%–50%) | Low-level mosaic |
| HM1 (03) | 6 | C | +4 (50%–70%) | High-level mosaic |
| HM2 (06) | 5 | B | +8 (50%–70%) | High-level mosaic |
| HM3 (14) | 5 | B | +19 (50%–70%) | High-level mosaic |
| HM4 (18) | 5 | C | −20 (50%–70%) | High-level mosaic |