Table 2.
MIC range and MIC90 of 13 antibiotics against 61 Brucella isolates.
| Antibiotic | MIC (μg/mL) | Classification of isolates (%) | Breakpoints (μg/mL) | |||||
|---|---|---|---|---|---|---|---|---|
| Range | M90 | S | I | R | S | I | R | |
| Azithromycin | 1–64 | 64 | 13.1 (8) | 0 | 86.9 (53) | ≤4 | – | >4 |
| Cefepime | 0.25–2 | 1 | 34.4 (21) | 0 | 65.6 (40) | ≤2 | – | >2 |
| Cefoperazone/sulbactam (2/1) | 0.5/0.25–8/4 | 4/8 | 72.1 (44) | 0 | 27.9 (17) | ≤2 | – | >2 |
| Cefotaxime | 0.25–2 | 1 | 96.7 (59) | 0 | 3.3 (2) | ≤2 | – | >2 |
| Trimethoprim/sulfamethoxazole (1/19) | 1/19–4/76 | 4/76 | 98.4 (60) | 0 | 1.6 (1) | ≤0.5/9.5 | 1/19–2/38 | >4/76 |
| Rifampin | 0.5–2 | 1 | 75.4 (46) | 24.6 (15) | 0 | ≤1 | 2 | >4 |
| Doxycycline | 0.12–0.24 | 0.12 | 100 (61) | 0 | ≤1 | – | >1 | |
| Tetracycline | 0.064–1 | 0.5 | 100 (61) | 0 | 0 | ≤2 | 4 | >8 |
| Minocycline | 0–0.032 | 0.032 | 100 (61) | 0 | 0 | ≤1 | – | >2 |
| Levofloxacin | 0.125–1 | 0.5 | 100 (61) | 0 | 0 | ≤2 | – | >2 |
| Ciprofloxacin | 0.5–1 | 1 | 100 (61) | 0 | 0 | ≤1 | – | >1 |
| Gentamicin | 0.5–1 | 1 | 100 (61) | 0 | 0 | ≤4 | – | >4 |
| Streptomycin | 2–4 | 4 | 100 (61) | 0 | 0 | ≤8 | – | >8 |
I, intermediate susceptibility; R, resistant; S, susceptible.