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. 2023 Apr 14;14:1148185. doi: 10.3389/fneur.2023.1148185

Table 4.

Comparison of NRI and IDI models for predicting the 1-year mortality in patients with ischemic stroke.

Index Developing cohort Verification cohort
Estimate 95% CI p value Estimate 95% CI p value
NRI (vs. GCS) 0.529 0.454–0.604 <0.001 0.265 0.160–0.369 <0.001
NRI (vs. SOFA) 0.473 0.395–0.551 <0.001 0.650 0.536–0.764 <0.001
NRI (vs. APS III) 0.361 0.288–0.434 <0.001 0.281 0.175–0.387 <0.001
NRI (vs. LODS) 0.278 0.202–0.353 <0.001 0.251 0.146–0.356 <0.001
NRI (vs. SAPS II) 0.247 0.174–0.319 <0.001 0.249 0.148–0.349 <0.001
NRI (vs. OASIS) 0.305 0.234–0.375 <0.001 0.195 0.100–0.290 <0.001
IDI (vs. GCS) 0.207 0.184–0.231 <0.001 0.157 0.120–0.193 <0.001
IDI (vs. SOFA) 0.200 0.174–0.226 <0.001 0.206 0.170–0.241 <0.001
IDI (vs. APS III) 0.151 0.126–0.175 <0.001 0.137 0.100–0.173 <0.001
IDI (vs. LODS) 0.156 0.131–0.182 <0.001 0.142 0.106–0.178 <0.001
IDI (vs. SAPS II) 0.120 0.097–0.143 <0.001 0.122 0.088–0.155 <0.001
IDI (vs. OASIS) 0.144 0.121–0.166 <0.001 0.126 0.094–0.158 <0.001

NRI, net reclassification index; IDI, integrated discrimination improvement; CI, confidence interval; GCS, Glasgow coma score; SOFA, sequential organ failure assessment; APS III, acute physiology score III; LODS, logistic organ dysfunction system; SAPS II, simplified acute physiology score II; OASIS, oxford acute severity of illness score. Cutoff: 0, 0.2, 0.4, 1.