TABLE 3.

Role of LINC00511 in lung cancer.

Cancer type	Expression/Role	Samples/Assessed cell lines	Pathways	Targets/Regulators	Function	Ref
Lung Squamous Cell Carcinoma (LUSC)	Upregulated/Oncogene	SK-MES-1, H226, 16-HBE	LINC00511/miR-150-5p/TADA1 axis	miR-150-5p/TADA1	A plan for the therapeutic targeting of LINC00511 in LUSC should be developed, because it stimulates the advancement of LUSC.	Wu et al. (2020)
Lung Adenocarcinoma (LUAD)	Upregulated/Oncogene	45 LAC tissues and corresponding adjacent normal lung tissues/BEAS‐2B, H1299, A549	PKM2 signaling pathway	miR-625-5p/PKM2	By influencing miR-625-5p/PKM2, LINC00511 was found to be engaged in the evolution of LAC, demonstrating that LINC00511/miR-625-5p/PKM2 may represent interesting treatment targets for LUAC.	Xue and Zhang (2020)
	Upregulated/Oncogene	40 TNTPs/A549, Calu-3, BEAS-2B, DV-90, PC-9	LINC00511/miR-195-5p/GCNT3 axis	miR-195-5p/GCNT3	By suppressing miR-195-5p, LINC00511 reduction encourages GCNT3 production, and as a result, supports the malignant growth of LUAD.	Zhang et al. (2022)
	Upregulated/Oncogene	A549/DDP, 16HBE	LINC00511/miR-182/BIRC5 axis	miR-182-3p/BIRC5	After injection of cisplatin (DDP), LINC00511 silencing prevents the growth of A549/DDP cells into tumors. In order to understand the mechanism of gained DDP tolerance, this research offers a unique LINC00511/miR-182/BIRC5 model	Zhu et al. (2022)
	Upregulated/Oncogene	35 TNTPs/A549, PC9, BEAS-2B	Linc00511/miR-126-5p/miR-218-5p/COL1A1 axis, PIK3/AKT pathway	miR-126-5p, miR-218-5p/COL1A1	By targeting miR-126-5p and miR-218-5p, LINC00511 influences COL1A1 production, encouraging cancerous cell growth and motility. LINC00511 could be a viable treatment approach for LUAD.	Wang et al. (2022)