Table 1B.
Glioneuronal and neuronal tumors | ||||
---|---|---|---|---|
MAPK pathway alteration | Ganglioglioma (126) | Desmoplastic infantile ganglioglioma/astrocytoma (127, 128) | Diffuse leptomeningeal glioneuronal tumor (21, 129, 130) | Multinodular and vacuolating neuronal tumor (21) |
FGFR1/2 mutation | 5% | + | ||
FGFR1/2 fusion | 7.5% | + | ||
NTRK1/2/3 fusion | 6% | + | ||
MET fusion | ||||
ROS1 fusion | ||||
KRAS SNV | 5% | |||
NF1 loss | 2.5% | |||
BRAF V600E | 45% | 30% | + | |
Other BRAF SNV | 12.5% | 30% | + | |
KIAA1569::BRAF fusion | 5% | 72% | ||
Other BRAF fusion | 5% | |||
CRAF fusion | 2.5% | + | ||
ERK/MAP2K1 SNV | + |
+, reported cases.