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. 2023 Apr 14;13:1154246. doi: 10.3389/fonc.2023.1154246

Table 1B.

MAPK pathway alterations by tumor type continued.

Glioneuronal and neuronal tumors
MAPK pathway alteration Ganglioglioma (126) Desmoplastic infantile ganglioglioma/astrocytoma (127, 128) Diffuse leptomeningeal glioneuronal tumor (21, 129, 130) Multinodular and vacuolating neuronal tumor (21)
FGFR1/2 mutation 5% +
FGFR1/2 fusion 7.5% +
NTRK1/2/3 fusion 6% +
MET fusion
ROS1 fusion
KRAS SNV 5%
NF1 loss 2.5%
BRAF V600E 45% 30% +
Other BRAF SNV 12.5% 30% +
KIAA1569::BRAF fusion 5% 72%
Other BRAF fusion 5%
CRAF fusion 2.5% +
ERK/MAP2K1 SNV +

+, reported cases.