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. 2023 Apr 14;14:1126154. doi: 10.3389/fimmu.2023.1126154

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Copyright © 2023 Alphonse, Duong, Tam and Yeung

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mercury exacerbates coronary artery disease in LCWE-injected murine model of KD. C57BL/6 mice were injected either with HgCl2 alone (s.c., 1.25mg/Kg body weight), LCWE alone (i.p., 1 mg/mouse) or with both LCWE and HgCl2. Heart sections were prepared 28 days later and stained with haematoxylin and eosin to evaluate the presence of coronary artery inflammation. LCWE-injected and treated with HgCl2 mice exhibited more intense and concentrated cellular infiltrates in comparison to mice injected only with either HgCl2 or LCWE. (200x magnification).