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. 2023 Apr 10;12(8):2802. doi: 10.3390/jcm12082802

Table 5.

Results of multivariate analyses, possible predictors of hyponatremia and hypernatremia.

Characteristics Coefficient SE CI-Min CI-Max p OR CI95 Lower CI95 Upper p
Predictors of hyponatremia
Age 0.02 0.00 0.01 0.03 0.0017 1.02 1.01 1.03 0.0017
HR 0.01 0.00 0.00 0.02 0.0177 1.01 1.00 1.02 0.0177
Consciousness 0.17 0.19 −0.19 0.54 0.3538 1.19 0.82 1.72 0.3538
Hypertension −0.27 0.19 −0.64 0.09 0.1458 0.76 0.53 1.10 0.1458
DM 0.34 0.16 0.02 0.66 0.0376 1.40 1.02 1.93 0.0376
ACEI/ARB/ARNI 0.42 0.18 0.08 0.76 0.0170 1.52 1.08 2.15 0.0170
Beta-blockers 0.01 0.17 −0.33 0.36 0.9400 1.01 0.72 1.43 0.9400
Diuretics −0.04 0.19 −0.42 0.34 0.8228 0.96 0.66 1.40 0.8228
CRP 0.00 0.00 0.00 0.00 0.0045 1.00 1.00 1.00 0.0045
Creatinine 0.08 0.05 −0.02 0.18 0.0987 1.09 0.98 1.20 0.0987
CVD 0.12 0.17 −0.22 0.46 0.4904 1.13 0.80 1.58 0.4904
Predictors of hypernatremia
Age 0.02 0.01 0.00 0.03 0.051 1.02 1.00 1.03 0.0510
SBP −0.02 0.01 −0.04 0.00 0.026 0.98 0.96 1.00 0.0263
DBP 0.02 0.01 0.00 0.05 0.090 1.02 1.00 1.05 0.0896
Consciousness 2.14 0.29 1.58 2.71 0.000 8.54 4.83 15.09 0.0000
Anticoagulants 0.44 0.32 −0.18 1.06 0.163 1.55 0.84 2.89 0.1629
CRP 0.00 0.00 0.00 0.01 0.028 1.00 1.00 1.01 0.0277
CVD −0.10 0.29 −0.67 0.47 0.728 0.90 0.51 1.60 0.7279

HR—heart rate; DM—diabetes mellitus; ACEI—angiotensin—converting enzyme inhibitor; ARB—angiotensin II receptor blocker; ARNI—angiotensin receptor—nephrilysin inhibitor; CRP—C reactive protein; CVD—cardiovascular disease; SBP—systolic blood pressure; DBP—diastolic blood pressure.