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Immunohistochemical staining of DT in experimental groups in cardiac tissue (×400). DT expression levels were significantly elevated in DOX-treated rats while CGA-treated rats demonstrated a significant decline in DT expression. Arrowhead: Intensity of immunoreactivity. (A) Control, (B) CGA, (C) DOX, and (D) DOX + CGA. Data are presented as the means ± SD. CGA: Chlorogenic acid (100 mg/kg); DOX: Doxorubicin (15 mg/kg); DT: dityrosine.
