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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1990 Jan;53(1):11–15. doi: 10.1136/jnnp.53.1.11

CT, MR and SPECT imaging in temporal lobe epilepsy.

R Duncan 1, J Patterson 1, D M Hadley 1, P Macpherson 1, M J Brodie 1, I Bone 1, A P McGeorge 1, D J Wyper 1
PMCID: PMC1014090  PMID: 2303825

Abstract

Cranial computed tomography (CT) with modified temporal lobe technique, 0.15T magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) were carried out on 30 patients with intractable temporal lobe epilepsy. Lateralising abnormalities were detected in 21/30 patients overall. Specific lesions were detected by CT in one patient and by MRI in seven patients (in one case bilateral). In addition CT detected asymmetry of the sylvian fissures or temporal horns in 10 patients, and MRI in eight patients. SPECT detected lateralising abnormalities in 19 patients (in five cases bilateral). It is concluded that low field MRI is superior to modified CT in demonstrating subtle structural lesions of the temporal lobe. Functional scanning with SPECT supports the evidence of origin of an epileptic focus in a substantial proportion of cases and may improve the selection of patients for surgery.

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Selected References

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  1. Abou-Khalil B. W., Siegel G. J., Sackellares J. C., Gilman S., Hichwa R., Marshall R. Positron emission tomography studies of cerebral glucose metabolism in chronic partial epilepsy. Ann Neurol. 1987 Oct;22(4):480–486. doi: 10.1002/ana.410220407. [DOI] [PubMed] [Google Scholar]
  2. Cahan L. D., Engel J., Jr Surgery for epilepsy: a review. Acta Neurol Scand. 1986 Jun;73(6):551–560. doi: 10.1111/j.1600-0404.1986.tb04599.x. [DOI] [PubMed] [Google Scholar]
  3. Engel J., Jr, Kuhl D. E., Phelps M. E., Crandall P. H. Comparative localization of epileptic foci in partial epilepsy by PCT and EEG. Ann Neurol. 1982 Dec;12(6):529–537. doi: 10.1002/ana.410120605. [DOI] [PubMed] [Google Scholar]
  4. Engel J., Jr The use of positron emission tomographic scanning in epilepsy. Ann Neurol. 1984;15 (Suppl):S180–S191. doi: 10.1002/ana.410150735. [DOI] [PubMed] [Google Scholar]
  5. Hougaard K., Oikawa T., Sveinsdottir E., Skinoj E., Ingvar D. H., Lassen N. A. Regional cerebral blood flow in focal cortical epilepsy. Arch Neurol. 1976 Aug;33(8):527–535. doi: 10.1001/archneur.1976.00500080005002. [DOI] [PubMed] [Google Scholar]
  6. Keränen T., Riekkinen P. Severe epilepsy: diagnostic and epidemiological aspects. Acta Neurol Scand Suppl. 1988;117:7–14. doi: 10.1111/j.1600-0404.1988.tb07997.x. [DOI] [PubMed] [Google Scholar]
  7. Kuhl D. E., Engel J., Jr, Phelps M. E., Selin C. Epileptic patterns of local cerebral metabolism and perfusion in humans determined by emission computed tomography of 18FDG and 13NH3. Ann Neurol. 1980 Oct;8(4):348–360. doi: 10.1002/ana.410080403. [DOI] [PubMed] [Google Scholar]
  8. Kuzniecky R., de la Sayette V., Ethier R., Melanson D., Andermann F., Berkovic S., Robitaille Y., Olivier A., Peters T., Feindel W. Magnetic resonance imaging in temporal lobe epilepsy: pathological correlations. Ann Neurol. 1987 Sep;22(3):341–347. doi: 10.1002/ana.410220310. [DOI] [PubMed] [Google Scholar]
  9. Lee B. I., Markand O. N., Wellman H. N., Siddiqui A. R., Park H. M., Mock B., Worth R. M., Edwards M. K., Krepshaw J. HIPDM-SPECT in patients with medically intractable complex partial seizures. Ictal study. Arch Neurol. 1988 Apr;45(4):397–402. doi: 10.1001/archneur.1988.00520280043014. [DOI] [PubMed] [Google Scholar]
  10. Lesser R. P., Modic M. T., Weinstein M. A., Duchesneau P. M., Lüders H., Dinner D. S., Morris H. H., 3rd, Estes M., Chou S. M., Hahn J. F. Magnetic resonance imaging (1.5 tesla) in patients with intractable focal seizures. Arch Neurol. 1986 Apr;43(4):367–371. doi: 10.1001/archneur.1986.00520040049018. [DOI] [PubMed] [Google Scholar]
  11. Neirinckx R. D., Canning L. R., Piper I. M., Nowotnik D. P., Pickett R. D., Holmes R. A., Volkert W. A., Forster A. M., Weisner P. S., Marriott J. A. Technetium-99m d,l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral blood perfusion. J Nucl Med. 1987 Feb;28(2):191–202. [PubMed] [Google Scholar]
  12. Olivier A. Risk and benefit in the surgery of epilepsy: complications and positive results on seizures tendency and intellectual function. Acta Neurol Scand Suppl. 1988;117:114–121. doi: 10.1111/j.1600-0404.1988.tb08012.x. [DOI] [PubMed] [Google Scholar]
  13. Podreka I., Lang W., Suess E., Wimberger D., Steiner M., Gradner W., Zeitlhofer J., Pelzl G., Mamoli B., Deecke L. Hexa-methyl-propylene-amine-oxime (HMPAO) single photon emission computed tomography (SPECT) in epilepsy. Brain Topogr. 1988 Fall;1(1):55–60. doi: 10.1007/BF01129340. [DOI] [PubMed] [Google Scholar]
  14. Sperling M. R., Wilson G., Engel J., Jr, Babb T. L., Phelps M., Bradley W. Magnetic resonance imaging in intractable partial epilepsy: correlative studies. Ann Neurol. 1986 Jul;20(1):57–62. doi: 10.1002/ana.410200110. [DOI] [PubMed] [Google Scholar]
  15. Theodore W. H., Dorwart R., Holmes M., Porter R. J., DiChiro G. Neuroimaging in refractory partial seizures: comparison of PET, CT, and MRI. Neurology. 1986 Jun;36(6):750–759. doi: 10.1212/wnl.36.6.750. [DOI] [PubMed] [Google Scholar]
  16. Theodore W. H., Fishbein D., Dubinsky R. Patterns of cerebral glucose metabolism in patients with partial seizures. Neurology. 1988 Aug;38(8):1201–1206. doi: 10.1212/wnl.38.8.1201. [DOI] [PubMed] [Google Scholar]
  17. Theodore W. H., Newmark M. E., Sato S., Brooks R., Patronas N., De La Paz R., DiChiro G., Kessler R. M., Margolin R., Manning R. G. [18F]fluorodeoxyglucose positron emission tomography in refractory complex partial seizures. Ann Neurol. 1983 Oct;14(4):429–437. doi: 10.1002/ana.410140406. [DOI] [PubMed] [Google Scholar]
  18. Triulzi F., Franceschi M., Fazio F., Del Maschio A. Nonrefractory temporal lobe epilepsy: 1.5-T MR imaging. Radiology. 1988 Jan;166(1 Pt 1):181–185. doi: 10.1148/radiology.166.1.3336676. [DOI] [PubMed] [Google Scholar]

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