Figure 6.

Orthology analysis of proteins containing C-type lectin-like domains in addition to other domains (CTLDcps). For a subset of the analyzed metazoan species, the conservation of several CTLDcps orthology groups is indicated: blue: orthologs including the CTL domain; gray: orthologs without the CTL domain. Three large categories were revealed: (A) orthology groups/gene families containing CTL domains across all metazoans and conserved in vertebrates; (B) gene families containing CTL domains in some metazoans (especially bivalves) while the CTL domains were lost from the ortholog genes of other species (completely lost in vertebrates); (C) CTLDcps gene families unique in bivalves, without clear orthology in other metazoan clades.