Figure 8.

Influence of celecoxib on A2058 cell invasion capacity from spheroid into hydrogel. Single spheroids of A2058 cells, transferred into an individual well of a 96-well plate containing hydrogel, were treated with vehicle alone (0.5% (v/v) DMSO) or with increasing concentrations of celecoxib (40, 80 or 100 µM), and the cell invasion capacity from spheroid in the surrounding hydrogel was monitored after 24, 48 and 72 h of treatment. Images are representative of three independent experiments. Magnification ×10.