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. 2023 Apr 20;11(4):874. doi: 10.3390/vaccines11040874

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Protective effects of Convacell^® in a Syrian hamster model. (A) Hamster body weight changes after SARS-CoV-2 challenge, M ± SEM. (B) Virus RNA quantification results presented as a Ct RT-PCR parameter, M ± SEM. (C) Lung weight coefficient, M ± SEM. (D) Sum of lung histology score (see Table S2 for details of score rubric), Me(Q1;Q3). Statistically significant differences (p < 0.05) according to the Mann–Whitney test with two-stage step-up are indicated: ‘#’ when compared to Intact group; ‘+’ when compared to Infected group; ‘*’ when compared to placebo-treated + infected group. More details of statistical analysis can be found in Tables S20 and S21.