Figure 2.

Data on the intracellular trafficking of ABCA3 variants: (A) localized in ER; (B) N-glycosylation; (C) localized in lysosomal compartments; (D) proteolytic cleavage. The green, dotted lines stand for ±1 nSD (fraction of WT nt). The purple, dotted lines stand for ±3 nSD (fraction of WT nt). The red, hollow circles represent data from this study. The red, solid circles represent data from our previous experiments. The red, semi-hollow triangles represent data from this study and the literature. The blue, semi-hollow triangles represent data from our previous experiments and the literature. The blue, solid triangles represent data from the literature. The black crosses represent that assays were not performed. Dark-grey shadow represents defective trafficking. The light-grey shadow represents impaired trafficking. No shadow represents normal trafficking. The assay code refers to Figure 1.